Trifluoromethanesulfonic Anhydride | 358-23-6

Cas No :

358-23-6

Synonyms :

Form :

Liquid

Molecular Weight :

282.14 G/mol

Molecular Formula :

C2F6O5S2

Boiling Point :

82 °c

Melting Point :

-60 °c

Flash Point :

80 °c

Solubility :

Reactive with water; soluble in organic solvents such as dichloromethane and toluene; not soluble in water

Description :

Trifluoromethanesulfonic Anhydride Supplier and Exporter for the USA

Chemical Bull is a trusted Trifluoromethanesulfonic Anhydride supplier, distributor, wholesaler, and exporter for the USA, supplying commercial requirements for pharmaceutical intermediates, agrochemical synthesis, fluorinated chemistry, fine chemicals, research applications, and specialty organic manufacturing.

Trifluoromethanesulfonic Anhydride, commonly known as Triflic Anhydride, is a highly reactive fluorinated sulfonic anhydride used mainly as a strong electrophilic reagent, triflation reagent, activating agent, and specialty synthesis intermediate. USA manufacturers commonly evaluate the material based on purity, moisture, acidity, impurity profile, packaging integrity, COA, SDS, and batch consistency.

Quick Answer

Trifluoromethanesulfonic Anhydride is mainly used in triflate formation, pharmaceutical intermediate synthesis, agrochemical intermediates, fluorinated organic chemistry, activation reactions, fine chemical manufacturing, and research synthesis. Submit a bulk enquiry with your required grade, purity, quantity, application, packaging, and USA delivery destination to receive availability and commercial pricing.


What Is Trifluoromethanesulfonic Anhydride?

Trifluoromethanesulfonic Anhydride is a highly reactive sulfonic acid anhydride derived from trifluoromethanesulfonic acid.

It is widely used in advanced organic synthesis because of its ability to introduce triflate functionality and activate suitable substrates for further transformation.

Trifluoromethanesulfonic Anhydride is commonly sourced by pharmaceutical intermediate manufacturers, agrochemical companies, fine chemical producers, specialty fluorine-chemistry businesses, research organizations, contract synthesis companies, distributors, and industrial procurement teams.


Trifluoromethanesulfonic Anhydride Product Information

Product Name: Trifluoromethanesulfonic Anhydride

Common Name: Triflic Anhydride

Chemical Type: Fluorinated Sulfonic Anhydride

Primary Functions: Triflation reagent, activating reagent, electrophilic reagent, fluorinated intermediate, and specialty synthesis raw material

Main Industries: Pharmaceuticals, agrochemicals, fine chemicals, fluorinated chemistry, research, and specialty organic synthesis

Commercial specifications can vary according to purity, moisture, acidity, color, and impurity profile. Because the material is highly reactive and moisture-sensitive, buyers should also review packaging integrity, storage requirements, COA, SDS, and technical specifications before commercial approval.


Trifluoromethanesulfonic Anhydride Applications for Industrial Manufacturing

Triflate Formation

Trifluoromethanesulfonic Anhydride is widely used as a triflation reagent in advanced organic synthesis.

It is commonly used to convert suitable functional groups into triflate derivatives that can serve as reactive intermediates in downstream transformations.

Pharmaceutical Intermediate Synthesis

Triflic Anhydride is used in selected pharmaceutical intermediate and active-ingredient synthesis routes.

Its strong activating capability makes it useful in advanced synthetic steps where controlled formation of reactive intermediates is required.

Agrochemical Intermediates

Trifluoromethanesulfonic Anhydride may be used in selected agrochemical intermediate manufacturing processes.

The required grade depends on reaction chemistry, impurity sensitivity, downstream purification, and final intermediate specifications.

Fluorinated Organic Chemistry

The product is widely used in selected fluorinated and high-value specialty chemical synthesis.

Its trifluoromethanesulfonyl functionality makes it useful in routes involving highly reactive fluorinated derivatives and specialty intermediates.

Activation Reactions

Trifluoromethanesulfonic Anhydride is used as a strong activating reagent in selected organic transformations.

Its use is generally associated with controlled laboratory and industrial synthesis environments where moisture exclusion and compatible equipment are important.

Fine Chemical Manufacturing

Triflic Anhydride is used in selected fine chemical and specialty intermediate manufacturing.

Manufacturers typically evaluate purity, moisture, reaction compatibility, impurity profile, and downstream process requirements before use.

Research and Development

High-purity Trifluoromethanesulfonic Anhydride is widely used in organic chemistry research and process development.

Research teams may use it in reaction development, route scouting, functional-group activation, and preparation of advanced intermediates.

Specialty Organic Synthesis

The product may also be used in selected complex molecule synthesis and specialty reaction systems.

The required specification should be matched to purity, moisture tolerance, reaction sensitivity, storage conditions, and downstream product requirements.


Why Manufacturers Source Trifluoromethanesulfonic Anhydride

Powerful Triflation Reagent

Triflic Anhydride is valued for its ability to introduce triflate functionality in suitable organic synthesis routes.

Strong Activation Capability

It is useful in selected transformations where a highly reactive electrophilic activating reagent is required.

Relevant to High-Value Intermediates

The product is widely associated with pharmaceutical, agrochemical, fluorinated, and fine chemical synthesis.

Useful for Advanced Organic Chemistry

Trifluoromethanesulfonic Anhydride is relevant to complex reaction development and specialty synthesis where controlled reactivity is important.

Suitable for Commercial Procurement

Triflic Anhydride can be sourced in commercial and recurring quantities for qualified manufacturers, specialty synthesis companies, distributors, and industrial procurement teams subject to applicable handling and transportation requirements.


Trifluoromethanesulfonic Anhydride Supplier for USA Manufacturers

When comparing a Trifluoromethanesulfonic Anhydride supplier for the USA, procurement teams should review purity, moisture, acidity, impurity profile, packaging integrity, batch consistency, COA, SDS availability, storage requirements, transportation controls, lead time, and recurring supply capability.

Chemical Bull supports commercial requirements for pharmaceutical intermediate manufacturers, agrochemical businesses, fine chemical companies, fluorinated chemical producers, contract synthesis organizations, research groups, distributors, and procurement teams across the United States.


Related Specialty and Fluorinated Chemicals

Manufacturers sourcing Trifluoromethanesulfonic Anhydride for advanced synthesis may also explore Trifluoroacetic Anhydride, Benzoyl Chloride, Pyridine, and Phenyl Isocyanate.

These related materials are commonly used across pharmaceutical intermediates, agrochemical synthesis, acylation, activation chemistry, fluorinated chemistry, and specialty organic manufacturing.


Trifluoromethanesulfonic Anhydride SDS and Documentation

Trifluoromethanesulfonic Anhydride is highly reactive, corrosive, and moisture-sensitive. USA buyers should review the latest supplier-issued Trifluoromethanesulfonic Anhydride SDS before handling, storage, transportation, processing, or commercial use.

Chemical Bull can provide available COA, SDS, product specifications, and technical documentation with commercial supply enquiries.

Buyers should confirm purity, moisture limits, packaging compatibility, storage conditions, workplace controls, material compatibility, transportation requirements, and application-specific specifications before commercial approval.


Buy Trifluoromethanesulfonic Anhydride in Bulk for the USA

Chemical Bull supports bulk Trifluoromethanesulfonic Anhydride requirements for pharmaceutical intermediate manufacturers, agrochemical businesses, fine chemical producers, specialty fluorine-chemistry companies, contract synthesis organizations, distributors, and industrial procurement teams.

Share your required Triflic Anhydride grade, purity, application, quantity, packaging preference, documentation requirements, and USA delivery destination to receive availability and a customized quotation.


Frequently Asked Questions

  1. What is Trifluoromethanesulfonic Anhydride?

    Trifluoromethanesulfonic Anhydride, also called Triflic Anhydride, is a highly reactive fluorinated sulfonic anhydride used mainly as a triflation and activating reagent in organic synthesis.

  2. What is Trifluoromethanesulfonic Anhydride used for?

    It is mainly used in triflate formation, pharmaceutical intermediates, agrochemical intermediates, fluorinated chemistry, activation reactions, fine chemical manufacturing, and research synthesis.

  3. Why is Triflic Anhydride used in organic synthesis?

    It is a powerful electrophilic reagent that can activate suitable substrates and form triflate derivatives used as reactive intermediates in advanced synthesis.

  4. What should buyers check before purchasing Trifluoromethanesulfonic Anhydride?

    Buyers should review purity, moisture, acidity, impurity profile, packaging integrity, COA, SDS, storage requirements, transportation controls, and batch consistency.

  5. Can Chemical Bull support bulk Trifluoromethanesulfonic Anhydride supply in the USA?

    Yes. Chemical Bull supports commercial requirements for pharmaceutical, agrochemical, fine chemical, fluorinated-chemistry, research, and specialty synthesis businesses across the United States, subject to applicable handling and transport requirements.