Trifluoroacetic Anhydride | 407-25-0

Cas No :

407-25-0

Form :

Liquid

Molecular Weight :

210.0 G/mol

Molecular Formula :

C4F6O3

Boiling Point :

76 °c

Melting Point :

-32 °c

Flash Point :

-20 °c

Solubility :

Reacts With Water; Soluble In Many Organic Solvents; Hydrolyzes In Water

Description :

Trifluoroacetic Anhydride Supplier and Exporter for the USA

Chemical Bull is a Trifluoroacetic Anhydride supplier, distributor, wholesaler, and exporter serving the USA, supporting commercial sourcing for fine chemical manufacturers, pharmaceutical intermediate producers, analytical laboratories, and specialty chemical businesses.

Trifluoroacetic Anhydride, commonly abbreviated as TFAA, has CAS No. 407-25-0 and molecular formula C4F6O3. It is used as a trifluoroacetylating reagent in chemical synthesis and analytical derivatization. USA buyers should evaluate assay, moisture, acid content, impurities, COA, SDS, and packaging.

Quick Answer

Trifluoroacetic Anhydride is a reactive fluorinated reagent used for trifluoroacetylation, selected organic synthesis, and gas chromatography derivatization. Also called TFAA, it has CAS number 407-25-0. USA buyers should specify synthesis or analytical-grade requirements, purity, quantity, compatible packaging, and delivery destination when requesting bulk pricing.


What Is Trifluoroacetic Anhydride?

Trifluoroacetic Anhydride is the acid anhydride of Trifluoroacetic Acid. Its structure is (CF3CO)2O, and another name is Bis(trifluoroacetic) Anhydride.

It reacts with suitable functional groups to introduce a trifluoroacetyl group. Its application depends on substrate chemistry and the intended synthesis or analytical method.

TFAA and Trifluoroacetic Acid are different compounds. Buyers should confirm the product name and CAS number before placing an order.


Product Information

Product Name: Trifluoroacetic Anhydride

Common Abbreviation: TFAA

CAS Number: 407-25-0

Molecular Formula: C4F6O3


Trifluoroacetic Anhydride Applications

Trifluoroacetylation

TFAA is used as a trifluoroacetylating reagent for suitable compounds containing reactive functional groups. Manufacturers should qualify the grade against their synthesis requirements and impurity limits.

Fine Chemical Synthesis

Trifluoroacetic Anhydride is used in selected fine chemical and specialty intermediate synthesis routes. Its suitability depends on reaction compatibility and downstream product specifications.

Gas Chromatography Derivatization

Qualified analytical grades are used for GC sample derivatization. Laboratories should confirm reagent purity, background impurities, and suitability for their validated analytical method.

Specialty Molecule Preparation

TFAA has documented use in selected nucleoside derivative synthesis. This application requires process-specific qualification and does not establish suitability for direct pharmaceutical use.


Why Buyers Source Trifluoroacetic Anhydride

Defined Acylating Function

TFAA provides trifluoroacetyl functionality for compatible synthesis and derivatization processes.

Synthesis and Analytical Applications

Different grades serve chemical manufacturing and laboratory derivatization requirements.

Grade-Specific Quality Control

Assay, moisture, acid content, and impurity limits should match the intended application. A synthesis grade should not automatically be treated as an analytical derivatization grade.

Bulk and Repeat Procurement

Procurement teams can communicate approved specifications, recurring quantities, packaging preferences, and delivery schedules when assessing supply.


Trifluoroacetic Anhydride Supplier for USA Buyers

When comparing a Trifluoroacetic Anhydride supplier for the USA, buyers should review chemical identity, assay and test method, moisture, Trifluoroacetic Acid content, relevant impurities, batch consistency, and packaging compatibility.

Chemical Bull supports sourcing enquiries from fine chemical manufacturers, pharmaceutical intermediate businesses, analytical laboratories, distributors, and industrial bulk buyers across the United States.

Confirm available grades, minimum order quantity, technical documentation, packaging options, and delivery lead time during quotation.


Related Synthesis Chemicals

Buyers sourcing fluorinated reagents and acylating materials may also explore Trifluoroacetic Acid, Acetic Anhydride, and Propionic Anhydride.

These chemicals differ in reactivity and the groups they introduce. Selection should follow the intended reaction and approved technical specifications.


Trifluoroacetic Anhydride SDS and Documentation

Trifluoroacetic Anhydride is a corrosive, moisture-reactive reagent. Contact with water forms Trifluoroacetic Acid. Handling, ventilation, storage, and transportation should follow the latest supplier-issued Trifluoroacetic Anhydride SDS.

Request the available COA, SDS, TDS, and product specifications with your enquiry. Confirm grade suitability, impurity limits, moisture protection, packaging compatibility, and storage requirements before purchasing.


Buy Trifluoroacetic Anhydride in Bulk for the USA

For bulk Trifluoroacetic Anhydride pricing, share your required grade, assay, moisture and acid limits, application, quantity, recurring demand, and packaging preference. Include your USA delivery city and ZIP code.

Request a Trifluoroacetic Anhydride quotation from Chemical Bull for USA delivery, grade confirmation, documentation, packaging, and commercial pricing.


Frequently Asked Questions

  1. What is Trifluoroacetic Anhydride?

    Trifluoroacetic Anhydride, or TFAA, is a fluorinated acid anhydride with CAS number 407-25-0 and molecular formula C4F6O3.

  2. What is Trifluoroacetic Anhydride used for?

    It is used for trifluoroacetylation, selected fine chemical synthesis, specialty molecule preparation, and GC derivatization with a suitable analytical grade.

  3. Is TFAA the same as Trifluoroacetic Acid?

    No. TFAA is Trifluoroacetic Anhydride, while Trifluoroacetic Acid is commonly abbreviated as TFA. They have different compositions and application requirements.

  4. Which TFAA grade should USA buyers request?

    Specify whether the material is intended for chemical synthesis or analytical derivatization. Review assay, moisture, acid content, and relevant impurities before approval.

  5. How can I request bulk TFAA pricing for the USA?

    Send Chemical Bull your required specifications, application, quantity, packaging preference, and USA delivery ZIP code to request availability and commercial pricing.